Article
Direct phenotyping of human apolipoprotein E in plasma: application to population frequency distribution in Paris (France).
Human heredity - 1 Jan 2000
Bailleul S, Couderc R, Landais V, Lefèvre G, Raichvarg D, Etienne J
Abstract excerpt
Apolipoprotein E (Apo E) is a component of VLDL and HDL and plays a significant role in the regulation of cholesterol concentration. An improvement in isoelectric focusing for Apo E phenotyping is presented: the plasma Apo E was dissociated from lipoproteins by the use of Tween 20; the optimal concentration of type V neuraminidase was determined (1 U/ml); up to 48 samples were analyzed per plate and revealed by...
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