Article
Apolipoprotein E allelic frequency in elderly smokers.
American journal of medical genetics - 26 Feb 1998
Bowman E D, Brömeke B, Lensing W, Shields P G
Abstract excerpt
Susceptibility genes for human diseases (e.g., cancer and atherosclerosis) increase disease risk by altering the metabolic activation of exogenous (e.g., carcinogens) and endogenous (e.g., cholesterol) compounds. The function of these genes, and subsequent risk, can be adversely affected by polymorphisms. This study tests the hypothesis that if specific genetic polymorphisms are related to mortality, then in...
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