Article
Genotypes and phenotypes for apolipoprotein E and Alzheimer disease in the Honolulu-Asia aging study.
Clinical chemistry - 1 Oct 2000
Kardaun J W, White L, Resnick H E, Petrovitch H, Marcovina S M, Saunders A M, Foley D J, Havlik R J
Abstract excerpt
BACKGROUND: The utility of apolipoprotein E (ApoE) type as an indicator of genetic susceptibility to Alzheimer disease (AD) depends on the reliability of typing. Although ApoE protein isoform phenotyping is generally assumed equivalent to genotyping from DNA, phenotype-genotype differences have been reported. METHODS: ApoE genotype and phenotype results were examined for 3564 older (ages 71-93 years)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.