Article
The kissing hairpin sequence promotes recombination within the HIV-I 5' leader region.
The Journal of biological chemistry - 28 Sept 2001
Balakrishnan M, Fay P J, Bambara R A
Abstract excerpt
The role of RNA-RNA template interactions in facilitating recombination during reverse transcription of minus strand DNA has been examined. The tested hypothesis is that template switching by reverse transcriptase is promoted at sites where homologous regions of two RNAs are brought in close proximity via stable intertemplate interactions. Frequency and distribution of template switching between homologous donor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
