Article
Dimer initiation signal of human immunodeficiency virus type 1: its role in partner selection during RNA copackaging and its effects on recombination.
Journal of virology - 1 Apr 2007
Moore Michael D, Fu William, Nikolaitchik Olga, Chen Jianbo, Ptak Roger G, Hu Wei-Shau
Abstract excerpt
Frequent human immunodeficiency virus type 1 (HIV-1) recombination occurs during DNA synthesis when portions of the two copackaged RNAs are used as templates to generate a hybrid DNA copy. Therefore, the frequency of copackaging of genomic RNAs from two different viruses (heterozygous virion form...
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