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Article

Dimer initiation signal of human immunodeficiency virus type 1: its role in partner selection during RNA copackaging and its effects on recombination.

Journal of virology - 1 Apr 2007

Moore Michael D, Fu William, Nikolaitchik Olga, Chen Jianbo, Ptak Roger G, Hu Wei-Shau

Abstract excerpt

Frequent human immunodeficiency virus type 1 (HIV-1) recombination occurs during DNA synthesis when portions of the two copackaged RNAs are used as templates to generate a hybrid DNA copy. Therefore, the frequency of copackaging of genomic RNAs from two different viruses (heterozygous virion formation) affects the generation of genotypically different recombinants. We hypothesized that the selection of copackaged...

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Identifiers

PMID: 17267488
DOI: 10.1128/JVI.02589-06
PMCID: PMC1866129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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