Article
Serum lipid levels and M/L55 allele distribution of HDL paraoxonase gene in Saami and Finnish men.
International journal of circumpolar health - 1 Jan 2001
Malin R, Lehtinen S, Luoma P, Näyhä S, Hassi J, Koivula T, Lehtimäki T
Abstract excerpt
Paraoxonase (PON) is an antioxidative enzyme, which eliminates lipid peroxides. The mutation in codon 55 of PON1 gene causes a change of methionine (M-allele) to leucine (L-allele) and influences PON activity. The Saami are a population living in the northern part of Fennoscandia. In previous studies their death rate from coronary artery disease (CAD) was found to be low. We compared PON M/L55 allele frequencies...
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