Article
Paraoxonase1 polymorphism Leu-Met55 is associated with cerebral infarction in Japanese population.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jun 2003
Ueno Takahiro, Shimazaki Emi, Matsumoto Taro, Watanabe Hideyuki, Tsunemi Akiko, Takahashi Yumiko, Mori Mayumi, Hamano Rumi, Fujioka Toshiyuki, Soma Masayoshi, Matsumoto Koichi, Kanmatsuse Katsuo
Abstract excerpt
BACKGROUND: Paraoxonase1 (PON1) is HDL-associated ester hydrolase which has been shown to prevent LDL and HDL oxidation in vitro. PON1-coding region has two common polymorphisms (M/L55 and A/B192) that influence PON activity. We examined whether these polymorphisms relates with the incidence of c...
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