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Article

A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies.

Statistics in medicine - 15 Jan 2006

Song Kijoung, Elston Robert C

Abstract excerpt

We present a new method for fine-mapping a disease susceptibility locus using a case-control design. The new method, termed the 'weighted average (WA) statistic', averages the Cochran-Armitage (CA) trend test statistic and the difference between the Hardy Weinberg disequilibrium test statistics (the HWD trend) for cases and controls. The main features of the WA statistic are that it mitigates against the...

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PMID: 16220513
DOI: 10.1002/sim.2350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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