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Genetic and environmental contributions to platelet aggregation: the Framingham heart study.

Circulation - 26 Jun 2001

O'Donnell C J, Larson M G, Feng D, Sutherland P A, Lindpaintner K, Myers R H, D'Agostino R A, Levy D, Tofler G H

Abstract excerpt

BACKGROUND: Platelet aggregation plays an important role in arterial thrombosis in coronary heart disease, stroke, and peripheral arterial disease. However, the contribution of genetic versus environmental influences on interindividual variation in platelet aggregability is poorly characterized. METHODS AND RESULTS: We studied the heritability of platelet aggregation responses in 2413 participants in the...

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PMID: 11425767
DOI: 10.1161/01.cir.103.25.3051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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