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Article

Heritability of platelet function in families with premature coronary artery disease.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2007

Bray P F, Mathias R A, Faraday N, Yanek L R, Fallin M D, Herrera-Galeano J E, Wilson A F, Becker L C, Becker D M

Abstract excerpt

BACKGROUND: Variations in platelet function among individuals may be related to differences in platelet-related genes. The major goal of our study was to estimate the contribution of inheritance to the variability in platelet function in unaffected individuals from white and African American families with premature coronary artery disease. METHODS: Platelet reactivity, in the absence of antiplatelet agents, was...

Topics

Adult
Blood Platelets
Coronary Artery Disease
Family Health
Female
Fibrinogen
Genotype
Humans
Male
Middle Aged
Platelet Aggregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Thrombosis

Thromboxane B2

von Willebrand Factor

Source

Identifiers

PMID: 17663734
DOI: 10.1111/j.1538-7836.2007.02618.x

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17663734-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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