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Article

The GNB3 C825T polymorphism influences platelet aggregation in human whole blood.

Pharmacogenetics and genomics - 1 Jan 2012

Dusse Fabian, Frey Ulrich H, Bilalic Adisa, Dirkmann Daniel, Görlinger Klaus, Siffert Winfried, Peters Jürgen

Abstract excerpt

BACKGROUND: Platelet aggregation varies among individuals; and genetic factors may alter platelet activation through G-protein-coupled receptors, thus influencing results of point-of-care platelet aggregometry in whole blood. We tested the hypothesis that the C825T polymorphism of the gene GNB3 encoding the G-protein β-3 subunit and the platelet GPIIIa Pl(A1)/(A2) polymorphism of the glycoprotein IIIa influence...

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Source

Identifiers

PMID: 22082654
DOI: 10.1097/FPC.0b013e32834e1674

Genes

GNB3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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