Article
[Polymorphism of the apolipoprotein E gene (APOE) in the populations of Russia and neighboring countries].
Genetika - 1 Oct 2007
Borinskaia S A, Kal'ina N R, Sanina E D, Kozhekbaeva Zh M, Gupalo E Iu, Garmash I V, Ogurtsov P P, Parshukova O N, Boĭko S G, Veselovskiĭ E M, Vershubskaia G G, Kozlov A I, Rogaev E I, Iankovskiĭ N K
Abstract excerpt
Allele and genotype frequencies for the locus encoding apolipoprotein E, involved in the regulation of lipid metabolism (APOE), were evaluated in 16 populations representing 12 ethnic groups (a total of 1103 subjects) from Russia and neighboring countries. In the populations examined, the frequencies of allele epsilon4, which is the risk factor of Alzheimer's disease and coronary heart disease, varied from less...
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