Article
Association between apolipoprotein E polymorphism and Alzheimer disease in Tehran, Iran.
Neuroscience letters - 25 Feb 2005
Raygani Asad Vaisi, Zahrai Mahine, Raygani Akbar Vaisi, Doosti Mahmood, Javadi Ebrahim, Rezaei Mansour, Pourmotabbed Tayebeh
Abstract excerpt
Epsilon 4 allele of apolipoprotein E (APOE-epsilon4) is a major risk factor for Alzheimer's disease (AD). The association of APOE allele frequencies with AD remains unknown in developing countries. We examined the frequency of APOE alleles in 105 patients with AD and 129 cognitively normal subjects of similar age and sex (control group), in Tehran, Iran. The APOE-epsilon4 allele frequency was significantly higher...
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