Article
Internally located signal peptides direct hepatitis C virus polyprotein processing in the ER membrane.
IUBMB life - 1 Jan 2001
Wu J Z
Abstract excerpt
An endoplasmic reticulum (ER) signal peptide is an amino acid sequence motif that directs the translocation of nascent polypeptides to the lumen of ER membrane. Most of known ER signal peptides are either N-terminal cleavable or internally uncleavable. In the structural protein region of hepatitis C virus (HCV) polyprotein, however, four internally located cleavable signal peptides are arranged in a tandem array....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.