Article

Processing of the hepatitis E virus polyprotein can be mediated by a cellular protease

2022-12-05

Abstract excerpt

The genomes of positive-sense RNA viruses encode polyproteins that are essential for controlling viral replication. These viral polyproteins must undergo proteolysis (also termed polyprotein processing) to generate functional protein units. This proteolysis can be performed by virally-encoded proteases as well as host cellular proteases, and is generally believed to be a key step in regulating viral replication. H...

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Literature Corpus work: deed56cf-8189-50d8-bc61-9079f06f9101
DOI: 10.1101/2022.12.05.519104

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