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Article

A new type of signal peptidase cleavage site identified in an RNA virus polyprotein.

The Journal of biological chemistry - 19 Mar 2010

Bintintan Ioana, Meyers Gregor

Abstract excerpt

Pestiviruses, a group of enveloped positive strand RNA viruses belonging to the family Flaviviridae, express their genes via a polyprotein that is subsequently processed by proteases. The structural protein region contains typical signal peptidase cleavage sites. Only the site at the C terminus of the glycoprotein E(rns) is different because it does not contain a hydrophobic transmembrane region but an...

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Identifiers

PMID: 20093364
DOI: 10.1074/jbc.M109.083394
PMCID: PMC2838279

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Source receipt: pubmed, retrieved 7 Sept 2026.

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