Article
hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif.
Experimental cell research - 1 Jul 2001
McVey Ward D, Radisky D, Scullion M A, Tuttle M S, Vaughn M, Kaplan J
Abstract excerpt
Vps41p, the protein encoded by the yeast gene VPS41, has been shown to mediate formation of AP-3 transport vesicles from the Golgi apparatus and to facilitate the docking and fusion of lysosomal vesicles. Although both of these activities involve transient association with membrane structures, the mechanisms that mediate those interactions have not been determined. Orthologues of VPS41 have been identified in...
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