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Article

Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.

Journal of molecular biology - 21 Sept 2001

Scheuring S, Röhricht R A, Schöning-Burkhardt B, Beyer A, Müller S, Abts H F, Köhrer K

Abstract excerpt

The yeast Vps4 protein (Vps4p) is a member of the AAA protein family (ATPases associated with diverse cellular activities) and a key player in the transport of proteins out of a prevacuolar endosomal compartment. In human cells, we identified two non-allelic orthologous proteins (VPS4-A and VPS4-B) of yeast Vps4p. The human VPS4-A and VPS4-B proteins display a high degree of sequence identity to each other (80 %)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11563910
DOI: 10.1006/jmbi.2001.4917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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