Article
A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole.
Molecular biology of the cell - 1 Nov 1997
Rieder S E, Emr S D
Abstract excerpt
Protein transport to the lysosome-like vacuole in yeast is mediated by multiple pathways, including the biosynthetic routes for vacuolar hydrolases, the endocytic pathway, and autophagy. Among the more than 40 genes required for vacuolar protein sorting (VPS) in Saccharomyces cerevisiae, mutations in the four class C VPS genes result in the most severe vacuolar protein sorting and morphology defects. Herein, we...
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