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Article

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B.

Journal of cell science - 15 Jun 2004

Fujita Hideaki, Umezuki Yusuke, Imamura Kanako, Ishikawa Daisuke, Uchimura Seiko, Nara Atsuki, Yoshimori Tamotsu, Hayashizaki Yoshihide, Kawai Jun, Ishidoh Kazumi, Tanaka Yoshitaka, Himeno Masaru

Abstract excerpt

SKD1 belongs to the AAA-ATPase family and is one of the mammalian class E Vps (vacuolar protein sorting) proteins. Previously we have reported that the overexpression of an ATPase activity-deficient form of SKD1 (suppressor of potassium transport growth defect), SKD1(E235Q), leads the perturbation of membrane transport through endosomes and lysosomes, however, the molecular mechanism behind the action of SKD1 is...

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PMID: 15173323
DOI: 10.1242/jcs.01170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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