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Article

Palmitoylation determines the function of Vac8 at the yeast vacuole.

Journal of cell science - 15 Jun 2006

Subramanian Kanagaraj, Dietrich Lars E P, Hou Haitong, LaGrassa Tracy J, Meiringer Christoph T A, Ungermann Christian

Abstract excerpt

Palmitoylation stably anchors specific proteins to membranes, but may also have a direct effect on the function of a protein. The yeast protein Vac8 is required for efficient vacuole fusion, inheritance and cytosol-to-vacuole trafficking. It is anchored to vacuoles by an N-terminal myristoylation site and three palmitoylation sites, also known as the SH4 domain. Here, we address the role of Vac8 palmitoylation...

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Share to Cell Membrane
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Share to Lipoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Protein Processing, Post-Translational

Share to src Homology Domains

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Source

Identifiers

PMID: 16720644
DOI: 10.1242/jcs.02972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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