Article
Transformation effector and suppressor genes.
Journal of cellular biochemistry - 1 Jul 1991
Boylan M O, Zarbl H
Abstract excerpt
Much has been learned about the molecular basis of cancer from the study of the dominantly acting viral and cellular oncogenes and their normal progenitors, the proto-oncogenes. More recent studies have resulted in the isolation and characterization of several genes prototypic of a second class of cancer genes. Whereas oncogenes act to promote the growth of cells, members of this latter class of genes act to...
Topics
- Animals
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Humans
- Neoplasms
- Oncogenes
- Phenotype