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Article

Clinical significance of genome-wide minimally deleted regions in oral squamous cell carcinomas.

Genes, chromosomes & cancer - 1 May 2011

Chien Huei-Tzu, Liao Chun-Ta, Huang Shiang-Fu, Chen I-How, Liu Tsung-Yun, Jou Yuh-Shan, Wang Hung-Ming, Hsieh Ling-Ling

Abstract excerpt

Oral squamous cell carcinoma (OSCC) has the highest rate of increase among male cancers in Taiwan. An understanding of the molecular pathogenesis of this disease as well as the development of prognostic markers for the clinical management of this disease is very important. Thus, a systematic loss of heterozygosity (LOH) analysis was performed to define minimally deleted regions (MDRs) in 63 male OSCCs using 400...

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PMID: 21344537
DOI: 10.1002/gcc.20861

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