Article
TFIIS enhances transcriptional elongation through an artificial arrest site in vivo.
Molecular and cellular biology - 1 Jul 2001
Kulish D, Struhl K
Abstract excerpt
Transcriptional elongation by RNA polymerase II has been well studied in vitro, but understanding of this process in vivo has been limited by the lack of a direct and specific assay. Here, we designed a specific assay for transcriptional elongation in vivo that involves an artificial arrest (ARTAR) site designed from a thermodynamic theory of DNA-dependent transcriptional arrest in vitro. Transcriptional analysis...
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