Article
Inhibition of Borrelia burgdorferi-tick interactions in vivo by outer surface protein A antibody.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2001
Pal U, Montgomery R R, Lusitani D, Voet P, Weynants V, Malawista S E, Lobet Y, Fikrig E
Abstract excerpt
Borrelia burgdorferi outer surface protein (Osp) A is preferentially expressed by spirochetes in the Ixodes scapularis gut and facilitates pathogen-vector adherence in vitro. Here we examined B. burgdorferi-tick interactions in vivo by using Abs directed against OspA from each of the three major B. burgdorferi sensu lato genospecies: B. burgdorferi sensu stricto, Borrelia afzelii, and Borrelia garinii. Abs...
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