Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection of variant Borrelia burgdorferi isolates from mice immunized with outer surface protein A or B.

Infection and immunity - 1 May 1995

Fikrig E, Tao H, Barthold S W, Flavell R A

Abstract excerpt

A nonclonal population of Borrelia burgdorferi N40 (passage 3) that survived protective immunity following challenge inoculation of outer surface protein (Osp) A- or B-hyperimmunized mice were characterized for the molecular basis of evasion of immunity. Two of six B. burgdorferi isolates, cultured from OspA-immunized mice, had antigenic diversity in the carboxyl terminus of OspA and did not bind to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Molecular
Share to Genes, Bacterial
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoblotting

Share to Recombinant Proteins

Share to Selection, Genetic

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 7729870
DOI: 10.1128/iai.63.5.1658-1662.1995
PMCID: PMC173206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection of variant Borrelia burgdorferi isolates from mice immunized with outer surface protein A or B.PMID 7729870Read ↗

Stability of Borrelia burgdorferi outer surface protein C under immune selection pressure.Semantic proximity Read ↗

An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.Semantic proximity Read ↗

Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization.Semantic proximity Read ↗

Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization.Semantic proximity Read ↗

Borrelia burgdorferi escape mutants that survive in the presence of antiserum to the OspA vaccine are killed when complement is also present.Semantic proximity Read ↗

Inhibition of Borrelia burgdorferi-tick interactions in vivo by outer surface protein A antibody.Semantic proximity Read ↗

Immune sera to individual Borrelia burgdorferi isolates or recombinant OspA thereof protect SCID mice against infection with homologous strains but only partially or not at all against those of different OspA/OspB genotype.Semantic proximity Read ↗

Sequence variation in the outer-surface-protein genes of Borrelia burgdorferi.Semantic proximity Read ↗

Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype.Semantic proximity Read ↗

An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal <i>Borrelia burgdorferi</i> challengeSemantic proximity Read ↗

Molecular Analysis of Sequence Heterogeneity among Genes Encoding Decorin Binding Proteins A and B of <i>Borrelia burgdorferi</i> Sensu LatoSemantic proximity Read ↗

Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.