Article
Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway.
Molecular biology of the cell - 1 Jun 2009
Yudowski Guillermo A, Puthenveedu Manojkumar A, Henry Anastasia G, von Zastrow Mark
Abstract excerpt
Membrane trafficking is well known to regulate receptor-mediated signaling processes, but less is known about whether signaling receptors conversely regulate the membrane trafficking machinery. We investigated this question by focusing on the beta-2 adrenergic receptor (B2AR), a G protein-coupled receptor whose cellular signaling activity is controlled by ligand-induced endocytosis followed by recycling. We used...
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