Article
A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors.
The Journal of biological chemistry - 14 Nov 2003
Tanowitz Michael, von Zastrow Mark
Abstract excerpt
delta and micro opioid receptors are homologous G protein-coupled receptors that are differentially sorted between divergent degradative and recycling membrane pathways following agonist-induced endocytosis. Whereas delta opioid receptors are selectively sorted to lysosomes, micro opioid receptors recycle rapidly to the plasma membrane by a process that has been proposed to occur via bulk membrane flow. We have...
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