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Article

Rab11 regulates the recycling and lysosome targeting of beta2-adrenergic receptors.

Journal of cell science - 1 Jul 2004

Moore Robert H, Millman Ellen E, Alpizar-Foster Estrella, Dai Wenping, Knoll Brian J

Abstract excerpt

The pericentriolar recycling endosome (RE) may be an alternative compartment through which some beta2-adrenergic receptors (beta2ARs) recycle from early endosomes to the cell surface during prolonged exposure to agonist. For the transferrin receptor, CXCR2, and the M4-muscarinic acetylcholine receptor, trafficking through the RE and receptor recycling is regulated by the small GTPase rab11. The precise role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endosomes
Share to Guanosine Triphosphate
Share to Lipoproteins, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysosomes

Share to rab GTP-Binding Proteins

Share to Receptors, Adrenergic, beta-2

Share to Receptors, Interleukin-8B

Share to Transferrin

Source

Identifiers

PMID: 15190120
DOI: 10.1242/jcs.01168

Genes

CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies.Semantic proximity Read ↗

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