Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence that palmitoylation of carboxyl terminus cysteine residues of the human luteinizing hormone receptor regulates postendocytic processing.

Molecular endocrinology (Baltimore, Md.) - 1 Mar 2005

Munshi Utpal M, Clouser Christine L, Peegel Helle, Menon K M J

Abstract excerpt

Palmitoylation is a well-conserved posttranslational modification among members of the G protein-coupled receptor superfamily. The present study examined the role of palmitoylation in endocytosis and postendocytic trafficking of the human LH receptor (LHR). Palmitoylation of the LHR was determined by incorporation of [3H]palmitic acid into wild-type (WT) or mutant receptor in which the potential palmitoylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cysteine
Share to Endocytosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycine

Share to GTP-Binding Proteins

Share to Immunoprecipitation

Share to Palmitic Acid

Share to Palmitic Acids

Share to Receptors, LH

Source

Identifiers

PMID: 15539429
DOI: 10.1210/me.2004-0335

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence that palmitoylation of carboxyl terminus cysteine residues of the human luteinizing hormone receptor regulates postendocytic processing.PMID 15539429Read ↗

Palmitoylation of the luteinizing hormone/human chorionic gonadotropin receptor regulates receptor interaction with the arrestin-mediated internalization pathway.Semantic proximity Read ↗

Palmitoylation of human thyrotropin receptor: slower intracellular trafficking of the palmitoylation-defective mutant.Semantic proximity Read ↗

Functional and structural roles of conserved cysteine residues in the carboxyl-terminal domain of the follicle-stimulating hormone receptor in human embryonic kidney 293 cells.Semantic proximity Read ↗

The palmitoyltransferase of the cation-dependent mannose 6-phosphate receptor cycles between the plasma membrane and endosomes.Semantic proximity Read ↗

Inhibition of the receptor-mediated endocytosis of diferric transferrin is associated with the covalent modification of the transferrin receptor with palmitic acid.Semantic proximity Read ↗

The position of cysteine relative to the transmembrane domain is critical for palmitoylation of H1, the major subunit of the human asialoglycoprotein receptor.Semantic proximity Read ↗

The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.Semantic proximity Read ↗

Palmitoylation of estrogen receptors is essential for neuronal membrane signaling.Semantic proximity Read ↗

Palmitoylation of the V2 vasopressin receptor carboxyl tail enhances beta-arrestin recruitment leading to efficient receptor endocytosis and ERK1/2 activation.Semantic proximity Read ↗

Substitution of the cysteine 438 residue in the cytoplasmic tail of the glucagon-like peptide-1 receptor alters signal transduction activity.Semantic proximity Read ↗

Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway.Semantic proximity Read ↗

Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.