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Article

Association of BCL10 germ line polymorphisms on chromosome 1p with advanced stage testicular germ cell tumor patients.

Cancer letters - 18 Aug 2006

Inoue Takamitsu, Ito Takuo, Narita Shintaro, Horikawa Yohei, Tsuchiya Norihiko, Kakinuma Hideaki, Mishina Mutsuki, Nakamura Eijiro, Kato Tetsuro, Ogawa Osamu, Habuchi Tomonori

Abstract excerpt

The association between four BCL10 single nucleotide polymorphisms at codons 5, 8, 162, and intron 1 and the susceptibility or progression for germ cell tumors (GCTs) was investigated in 73 testicular GCT patients and 72 controls. GCT patients with metastatic disease were more likely to have a variant type allele of the polymorphisms at codon 5 (age-adjusted odds ratio (aOR)=6.25; 95% CI=1.09-35.83; P=0.040) and...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Linkage Disequilibrium

Share to Neoplasm Metastasis

Share to Neoplasms, Germ Cell and Embryonal

Share to Polymorphism, Single Nucleotide

Share to Testicular Neoplasms

Source

Identifiers

PMID: 16229939
DOI: 10.1016/j.canlet.2005.08.019

Genes

BCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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