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Article

Bcl10 is not a target for frequent mutation in human carcinomas.

British journal of cancer - 1 Jul 1999

Lambers A R, Gumbs C, Ali S, Marks J R, Iglehart J D, Berchuck A, Futreal P A

Abstract excerpt

The recently described Bcl10 gene has been suggested to be a major target gene for inactivation in a variety of human cancers. In order to further evaluate the role of this gene in human adult malignancies, we have analysed a series of carcinomas for mutations in the Bcl10 gene. We have screened a panel of 174 carcinoma samples in total, comprised of 47 breast, 36 epithelial ovarian, 36 endometrial, 12 cervical,...

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Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 10408401
DOI: 10.1038/sj.bjc.6690564
PMCID: PMC2363095

Genes

BCL10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Bcl10 is not a target for frequent mutation in human carcinomas.PMID 10408401Read ↗

BCL10 gene mutations rarely occur in lymphoid malignancies.Semantic proximity Read ↗

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BCL10 is not the gene inactivated by mutation in the 1p22 deletion region in mantle cell lymphoma.Semantic proximity Read ↗

Lack of BCL10 mutations in Hodgkin's disease-derived cell lines.Semantic proximity Read ↗

Analysis of Li-Fraumeni syndrome and Li-Fraumeni-like families for germline mutations in Bcl10.Semantic proximity Read ↗

Lack of BCL10 mutations in germ cell tumors and B cell lymphomas.Semantic proximity Read ↗

Infrequent BCL10 mutations in B-cell non-Hodgkin's lymphomas.Semantic proximity Read ↗

BCL10 is not a major target for frequent loss of 1p in testicular germ cell tumors.Semantic proximity Read ↗

BCL10 somatic mutations rarely occur in gastric lymphoma: detection of high frequency of polymorphisms in BCL10 coding region.Semantic proximity Read ↗

Low frequency of BCL10 gene mutations in B-cell non-Hodgkin's lymphoma.Semantic proximity Read ↗

Absence of Bcl10 gene mutations in Ewing's sarcomas.Semantic proximity Read ↗

BCL10 is rarely mutated in human prostate carcinoma, small-cell lung cancer, head and neck tumours, renal carcinoma and sarcomas. MPT Collaborators, St George's Hospital Collaborators.Semantic proximity Read ↗

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