Article
Infrequent BCL10 mutations in B-cell non-Hodgkin's lymphomas.
Japanese journal of cancer research : Gann - 1 Dec 1999
Takahashi H, Hosokawa Y, Suzuki R, Morishima Y, Nakamura S, Seto M
Abstract excerpt
The BCL10 gene was recently isolated from the breakpoint region of t(1;14)(p22;q32) in mucosa-associated lymphoid tissue (MALT) lymphomas. Somatic mutations of BCL10 were found in not only t(1;14)-bearing MALT lymphomas, but also a wide range of other tumors. To clarify the actual frequency and spectrum of BCL10 mutations in primary B-cell non-Hodgkin's lymphomas (NHL), we examined a total of 139 NHL cases...
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