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Article

PKCdelta is required for mitochondrial-dependent apoptosis in salivary epithelial cells.

The Journal of biological chemistry - 10 Aug 2001

Matassa A A, Carpenter L, Biden T J, Humphries M J, Reyland M E

Abstract excerpt

We report here that the novel protein kinase C isoform, PKCdelta, is required at or prior to the level of the mitochondria for apoptosis induced by a diverse group of cell toxins. We have used adenoviral expression of a kinase-dead (KD) mutant of PKCdelta to explore the requirement for PKCdelta in the mitochondrial-dependent apoptotic pathway. Expression of PKCdeltaKD, but not PKCalphaKD, in salivary epithelial...

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Source

Identifiers

PMID: 11369761
DOI: 10.1074/jbc.M100273200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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