Article
Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Oct 2000
Moskow J J, Gladfelter A S, Lamson R E, Pryciak P M, Lew D J
Abstract excerpt
CDC42 encodes a highly conserved GTPase of the Rho family that is best known for its role in regulating cell polarity and actin organization. In addition, various studies of both yeast and mammalian cells have suggested that Cdc42p, through its interaction with p21-activated kinases (PAKs), plays a role in signaling pathways that regulate target gene transcription. However, recent studies of the yeast pheromone...
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