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Article

Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice.

Circulation research - 11 May 2001

Wang H D, Xu S, Johns D G, Du Y, Quinn M T, Cayatte A J, Cohen R A

Abstract excerpt

Oxygen-derived free radicals are involved in the vascular response to angiotensin II (Ang II), but the role of NADPH oxidase, its subunit proteins, and their vascular localization remain controversial. Our purpose was to address the role of NADPH oxidase in the blood pressure (BP), aortic hypertrophic, and oxidant responses to Ang II by taking advantage of knockout (KO) mice that are genetically deficient in...

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PMID: 11349005
DOI: 10.1161/hh0901.089987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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