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Article

Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium.

Cardiovascular research - 1 Feb 2017

Shafique Ehtesham, Torina Anali, Reichert Karla, Colantuono Bonnie, Nur Nasifa, Zeeshan Khawaja, Ravichandran Vani, Liu Yuhong, Feng Jun, Zeeshan Khawaja, Benjamin Laura E, Irani Kaikobad, Harrington Elizabeth O, Sellke Frank W, Abid Md Ruhul

Abstract excerpt

AIMS: There are conflicting reports on the role of reactive oxygen species (ROS) i.e. beneficial vs. harmful, in vascular endothelium. Here, we aim to examine whether duration of exposure to ROS and/or subcellular ROS levels are responsible for the apparently paradoxical effects of oxidants on endothelium. METHODS AND RESULTS: We have recently generated binary (Tet-ON/OFF) conditional transgenic mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potential, Mitochondrial

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Source

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Identifiers

PMID: 28088753
DOI: 10.1093/cvr/cvw249
PMCID: PMC5340144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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