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Article

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus.

Nature genetics - 1 Oct 1994

Field L L, Tobias R, Magnus T

Abstract excerpt

To identify new loci predisposing to insulin-dependent diabetes mellitus (IDDM), we have investigated 250 families with more than one diabetic child. Affected sibling pair linkage analysis revealed strong evidence for an IDDM susceptibility locus near D15S107 on chromosome 15q26 (P = 0.0010) termed IDDM3. Families less predisposed through genes in the HLA region provided most of the evidence for linkage. In these...

Topics

Canada
Chromosome Mapping
Chromosomes, Human, Pair 15
Diabetes Mellitus, Type 1
Europe
Genetic Heterogeneity
Genetic Markers
Genetic Predisposition to Disease
HLA-DR Antigens
Humans
Lod Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7842018
DOI: 10.1038/ng1094-189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7842018-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus.PMID 7842018Read ↗

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