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Article

Overexpression of the transcriptional repressor FoxD3 prevents neural crest formation in Xenopus embryos.

Mechanisms of development - 1 May 2001

Pohl B S, Knöchel W

Abstract excerpt

Xenopus FoxD3 (XFD-6) is an intron-less gene initially expressed within the Spemann organizer and later in premigratory neural crest cells. Based upon sequence and expression pattern comparisons, it represents the Xenopus orthologue to zebrafish fkd6, chicken CWH-3 and mammalian HFH-2 (genesis). Early expression of FoxD3 is activated by the Wnt-pathway and inhibited by BMP signalling. Ectopic overexpression of...

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PMID: 11335115
DOI: 10.1016/s0925-4773(01)00334-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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