Article
Key basic helix-loop-helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development.
Developmental biology - 15 Apr 2008
Nakazaki Hiromichi, Reddy Anvesh C, Mania-Farnell Barbara L, Shen Yueh-Wei, Ichi Shunsuke, McCabe Christopher, George David, McLone David G, Tomita Tadanori, Mayanil C S K
Abstract excerpt
Pax3 is expressed early during embryonic development in spatially restricted domains including limb muscle, neural crest, and neural tube. Pax3 functions at the nodal point in melanocyte stem cell differentiation, cardiogenesis and neurogenesis. Additionally Pax3 has been implicated in migration and differentiation of precursor cell populations. Currently there are questions about how Pax3 regulates these diverse...
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