Article
Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.
Developmental biology - 1 Dec 2011
Wang Wen-Der, Melville David B, Montero-Balaguer Mercedes, Hatzopoulos Antonis K, Knapik Ela W
Abstract excerpt
The neural crest is a stem cell-like population exclusive to vertebrates that gives rise to many different cell types including chondrocytes, neurons and melanocytes. Arising from the neural plate border at the intersection of Wnt and Bmp signaling pathways, the complexity of neural crest gene regulatory networks has made the earliest steps of induction difficult to elucidate. Here, we report that tfap2a and...
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