Article
Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis.
Human immunology - 1 May 2001
Meddeb-Garnaoui A, Gritli S, Garbouj S, Ben Fadhel M, El Kares R, Mansour L, Kaabi B, Chouchane L, Ben Salah A, Dellagi K
Abstract excerpt
HLA-DRB1, -DQB1, TNFalpha, TNFbeta, HSP70-2 and HSP70-hom genetic polymorphisms were analyzed in 156 unrelated patients who developed mediterranean visceral leishmaniasis (MVL) due to Leishmania infantum, and 154 unrelated healthy controls, who have got asymptomatic infection with this parasite and were selected on the basis of a positive leishmanin skin test (LST). A significantly reduced frequency of HLA-DR2...
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