Article
Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis.
The Journal of experimental medicine - 1 Nov 1995
Cabrera M, Shaw M A, Sharples C, Williams H, Castes M, Convit J, Blackwell J M
Abstract excerpt
Recent studies have shown that mucocutaneous leishmaniasis (MCL), a severe and debilitating form of American cutaneous leishmaniasis (ACL) caused by Leishmania braziliensis infection, is accompanied by high circulating levels of tumor necrosis factor (TNF)-alpha. Analysis of TNF polymorphisms in...
Topics
- Adolescent
- Adult
- Alleles
- Base Sequence
- Child
- Female
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Introns
- Leishmaniasis, Mucocutaneous
- Lymphotoxin-alpha
- Male
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Genetic
- Risk
- Tumor Necrosis Factor-alpha