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Article

TGFB1 and IL8 gene polymorphisms and susceptibility to visceral leishmaniasis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2011

Frade Amanda Farage, Oliveira Lea Campos de, Costa Dorcas Lamounier, Costa Carlos Henrique Nery, Aquino Dorlene, Van Weyenbergh Johan, Barral-Netto Manoel, Barral Aldina, Kalil Jorge, Goldberg Anna Carla

Abstract excerpt

Visceral leishmaniasis (VL) or Kala-azar is a serious protozoan infectious disease caused by an obligate intracellular parasite. Cytokines have a major role in determining progression and severity of clinical manifestations in VL. We investigated polymorphisms in the TGFB1and IL8 genes, which are cytokines known to have a role in onset and severity of the disease. Polymorphisms at TGFB1 -509 C/T and +869 T/C, and...

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Source

Identifiers

PMID: 21376140
DOI: 10.1016/j.meegid.2011.02.014

Genes

TGFB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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