Article
Association analysis of human leukocyte antigen class II (DRB1) alleles with leprosy in individuals from São Luís, state of Maranhão, Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Dec 2012
Corrêa Rita da Graça Carvalhal Frazão, de Aquino Dorlene Maria Cardoso, Caldas Arlene de Jesus Mendes, Serra Humberto de Oliveira, Silva Fábio França, Ferreira Maxwellem de Jesus Costa, Santos Elton Jonh Freitas, Mesquita Emygdia Rosa Rêgo Barros Pires Leal
Abstract excerpt
Epidemiological studies have demonstrated that the variability of the clinical response to infection caused by Mycobacterium leprae is associated with host genetic factors. The present study investigated the frequency of human leukocyte antigen (HLA) class II (DRB1) alleles in patients with leprosy from São Luís, Maranhão, Brazil. A case-control study was performed in 85 individuals with leprosy and 85 healthy...
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