Article
The TLR2 and TLR4 gene polymorphisms in Moroccan visceral leishmaniasis patients.
Acta tropica - 1 Jun 2016
Ejghal Rajaâ, Hida Moustapha, Bennani Mounya Lahkim, Meziane Mariame, Aurag Rabia, Lemrani Meryem
Abstract excerpt
Visceral leishmaniasis (VL) is endemic in the Mediterranean basin and leads to the most severe form of Leishmania infection, lethal if left untreated. However, most infections are sub-clinical or asymptomatic, reflecting the influence of host genetic background on disease outcome. This study aimed to investigate possible association of TLR4 Asp299Gly, TLR4 Thr399Ile and TLR2 Arg753Gln polymorphisms with VL in...
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