Article
Association between the tumor necrosis factor locus and the clinical outcome of Leishmania chagasi infection.
Infection and immunity - 1 Dec 2002
Karplus Theresa M, Jeronimo Selma M B, Chang Haeok, Helms Bethany K, Burns Trudy L, Murray Jeffrey C, Mitchell Adele A, Pugh Elizabeth W, Braz Regina F S, Bezerra Fabiana L, Wilson Mary E
Abstract excerpt
A periurban outbreak of visceral leishmaniasis (VL) caused by the protozoan Leishmania chagasi is ongoing outside Natal, northeast Brazil. Manifestations range from asymptomatic infection to disseminated visceral disease. Literature reports suggest that both genetic and environmental factors influence the outcome of infection. Due to the association of the tumor necrosis factor (TNF) locus with other infectious...
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