Article
Role of HLA class II alleles in susceptibility to and protection from localized cutaneous leishmaniasis.
Human immunology - 1 Mar 2004
Olivo-Díaz Angélica, Debaz Héctor, Alaez Carmen, Islas Víctor Juárez, Pérez-Pérez Héctor, Hobart Oscar, Gorodezky Clara
Abstract excerpt
Localized cutaneous leishmaniasis (LCL) is the prevalent form of leishmaniasis in Mexico. It is limited to the skin; reversible upon treatment and the host cellular immune response is intact. Several genes that influence the expression of LCL have been described in the mouse. In humans, we, as well as others, have demonstrated that HLA-DQ3 antigens seem to play some role in host susceptibility. We therefore...
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