Article
Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam.
The Journal of infectious diseases - 15 Jan 2001
Dunstan S J, Stephens H A, Blackwell J M, Duc C M, Lanh M N, Dudbridge F, Phuong C X, Luxemburger C, Wain J, Ho V A, Hien T T, Farrar J, Dougan G
Abstract excerpt
The influence of genes of the major histocompatibility complex (MHC) class II and class III loci on typhoid fever susceptibility was investigated. Individuals with blood culture-confirmed typhoid fever and control subjects from 2 distinct geographic locations in southern Vietnam were genotyped for HLA-DRB1 and HLA-DQB1 alleles, the gene that encodes tumor necrosis factor (TNF)-alpha (TNFA [-238] and TNFA [-308]),...
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