Article
A region near the C-terminal end of Escherichia coli DNA helicase II is required for single-stranded DNA binding.
Journal of bacteriology - 1 Apr 1999
Mechanic L E, Latta M E, Matson S W
Abstract excerpt
The role of the C terminus of Escherichia coli DNA helicase II (UvrD), a region outside the conserved helicase motifs, was investigated by using three mutants: UvrDDelta107C (deletion of the last 107 C-terminal amino acids), UvrDDelta102C, and UvrDDelta40C. This region, which lacks sequence similarity with other helicases, may function to tailor UvrD for its specific in vivo roles. Genetic complementation assays...
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